Every Patient. Every Dollar. Protected.
Pharma performance in the next era comes down to one thing: How effectively you control costs while maximizing net revenue
As payer dynamics shift and affordability spend grows, traditional models fall short. GTN revenue protection closes the gap—driving cost control and protecting revenue.
Affordability spend is predicted to increase, with patients under pressure from all sides.
There is increased complexity and margin pressure which leads to:
- Escalating payer restrictions and utilization management
- Growth of accumulators and maximizers
- Accelerating GTN compression as the “GTN bubble” deflates
Why Copay Vendors Miss It
Traditional copay vendors often miss GTN leakage because their infrastructure was built to process claims and distribute funds, not to monitor how those funds interact with today’s increasingly complex payer dynamics.
#1 - They focus on transaction processing - not net revenue integrity.
#2 - They have limited visibility into Maximizer & Accumulator Programs.
#3 - Data is siloed across PBMs and plans, making it difficult to detect.
#4 - Legacy copay programs are built to react to claims, not built for predictive detection.
Copay vendors are optimized for administration, not revenue protection. In today’s environment — shaped by maximizers, accumulators, and complex PBM economics — that gap in visibility and analytics is where GTN leakage often hides.
Our Proven Impact
3M+
patients supported
$1B+
revenue protected
35K+
transactions tracked daily
150+
unique drug brands tracked
Better Patient Experience & Profitable Growth in a High-Cost Environment
Real-time GTN Revenue Protection for your leading drug brands.
How it Works
Purchase only the products that you need.
Pay based on the dollars you save.
Get support any time from your dedicated, in-house team of experts.
RIS Rx is trusted by the world’s leading pharmaceutical manufacturers.
"We expected addressing GTN leakage to be a cost center. Instead, it became a source of profitability."
- Pharma CFO
"RIS Rx's eBV technology is special and I don't need to micromanage them. They are always on it and always get right back to me."
— Director Vendor Management, Patient Support
"RIS Rx's customer service is outstanding. Their team always made time for us. I would re-implement using them."
— Director of Patient Access
"RIS Rx's flexibility and technology are great. They resolved issues with our prior vendor."
— VP of Commercial Operations
Future Proof Your Commercial Strategy with RIS Rx
Strengthen your drug cost containment strategy and unlock stronger GTN performance.
"We expected addressing GTN leakage to be a cost center. Instead, it became a source of profitability."
- Pharma CFO
20+
of the world's leading pharmaceutical manufacturers trust RIS Rx
150+
leading drug brands across all therapeutic areas
100
Net Promoter Score
RIS Rx offers real-time GTN Revenue Protection to the world's leading pharmaceutical manufacturers, ensuring that every dollar allocated for affordability reaches the right patient at the right time.
The Challenge: Drug Costs are Reshaping Pharma Strategy
Why Traditional Pharma Commercial Strategies are Falling Short
Most commercial strategies were built for a different environment—one with:
- - Less pricing pressure
- - Simpler access pathways
- - More predictable reimbursement
- - Reactive cost control
- - Lack of real-time visibility into GTN drivers
Revenue is lost faster than it can be optimized. GTN Revenue Protection helps with controlling costs and maximizing net revenue.
With the right strategy in place, manufacturers can:
- Better serve their patients
- Control copay spending
- Improve net sales and GTN performance
- Increase ROI across commercial investments
- Adapt faster to payer and market changes
All of this increases the risk of copay misuse, margin erosion, and reduced ROI on
commercial investments.
The result?
With RIS Rx, you can proactively manage rising costs and GTN risk—while protecting patient affordability programs in real time.