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Every Patient. Every Dollar. Protected.

Stop Copay Accumulator Leakage Before It Happens

RIS Rx helps pharmaceutical manufacturers identify, quantify, and prevent copay
accumulator exposure in real time
—protecting patient affordability programs and gross-to-net performance.

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The Problem

Across commercial insurance markets, copay accumulator programs are increasingly being adopted by employers and payers.

The result:

RIS Rx was built to solve this problem.

  • Copay assistance is depleted earlier than expected
  • Patients face unexpected pharmacy costs mid-year
  • Manufacturers experience increased GTN exposure
  • Affordability programs fail to deliver their intended impact
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Why Copay Vendors Miss It

Traditional copay vendors often miss GTN leakage because their infrastructure was built to process claims and distribute funds, not to monitor how those funds interact with today’s increasingly complex payer dynamics.

#1 - They focus on transaction processing - not net revenue integrity.

#2 - They have limited visibility into Maximizer & Accumulator Programs.

#3 - Data is siloed across PBMs and plans, making it difficult to detect.

#4 - Legacy copay programs are built to react to claims, not built for predictive detection.

Copay vendors are optimized for administration, not revenue protection. In today’s environment — shaped by maximizers, accumulators, and complex PBM economics — that gap in visibility and analytics is where GTN leakage often hides.

Our Proven Impact

3M+

patients supported

$1B+

revenue protected

35K+

transactions tracked daily

150+

unique drug brands tracked

Our Accumulator Solutions

PBM / Payer-based leakage solution

Benefit Patient Solution

Addresses maximizer and accumulator GTN leakage in real-time.

Real-time GTN Revenue Protection
for your leading drug brands.

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How it Works

Purchase only the products that you need.

Pay based on the dollars you save.

Get support any time from your dedicated, in-house team of experts.

RIS Rx is trusted by the world’s leading pharmaceutical manufacturers.

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"We expected addressing GTN leakage to be a cost center. Instead, it became a source of profitability."

- Pharma CFO

"RIS Rx's eBV technology is special and I don't need to micromanage them. They are always on it and always get right back to me."

— Director Vendor Management, Patient Support

"RIS Rx's customer service is outstanding. Their team always made time for us. I would re-implement using them."

— Director of Patient Access

"RIS Rx's flexibility and technology are great. They resolved issues with our prior vendor."

— VP of Commercial Operations

Uncover Your Accumulator Exposure

Most manufacturers cannot see their true copay accumulator exposure until it has already
impacted their affordability programs.

RIS Rx helps identify accumulator plans, quantify GTN risk, and protect patient affordability
programs in real time.

Give us 30 minutes and discover how much maximizer exposure may be impacting your
brand.

"We expected addressing GTN leakage to be a cost center. Instead, it became a source of profitability."

- Pharma CFO

20+

of the world's leading pharmaceutical manufacturers trust RIS Rx

150+

leading drug brands across all therapeutic areas

100

Net Promoter Score

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RIS Rx offers real-time GTN Revenue Protection to the world's leading pharmaceutical manufacturers, ensuring that every dollar allocated for affordability reaches the right patient at the right time.

Copay Accumulator Programs Are Reshaping Patient Affordability

The RIS Rx Approach

Identify Copay Accumulator Plans Before They Impact Your Program

RIS Rx provides real-time accumulator detection and exposure analytics so manufacturers can identify when patients are enrolled in copay accumulator plans or accumulator adjustment programs.

Our pharmacist-led platform helps teams:

  • - Identify accumulator insurance plans in real time
  • - Quantify accumulator-driven GTN exposure
  • - Understand payer behavior across healthcare accumulator programs

These programs prevent manufacturer copay assistance from counting toward a patient’s deductible or out-of-pocket maximum.

Instead of discovering accumulator exposure months later through retrospective reporting,
RIS Rx delivers
visibility and prevention at the moment of patient enrollment.

Real-Time Accumulator Detection
RIS Rx’s
Benefit Patient Solution (BPS) identifies patients enrolled in copay maximizer and accumulator plans in real time—giving manufacturers immediate visibility into maximizer-driven GTN exposure.

By analyzing patient benefit design at enrollment, BPS helps manufacturers:

  • Identify copay accumulator plans before first fill
  • Detect accumulator adjustment programs across insurance plans
  • Quantify the impact of accumulator programs on GTN performance

Instead of discovering maximizer impact months later, BPS delivers real-time visibility and protection for your copay programs.

Without clear visibility into accumulator plans and insurance accumulator behavior, manufacturers often discover the impact only after GTN costs have already increased.

Benefit Patient Solution (BPS)

Quick Rebate

Patient Reimbursement for Accumulator Plans

For patients affected by copay accumulator programs, RIS Rx’s QuickRebate solution enables manufacturers to reimburse eligible out-of-pocket costs directly.

This approach helps:

  • Restore affordability for patients impacted by accumulators
  • Maintain therapy adherence
  • Protect the intended value of manufacturer copay assistance

QuickRebate works alongside BPS to provide both accumulator detection and reimbursement protection.

Accumulator-focused reimbursement solution

QuickRebate

Delivers rapid reimbursement so co-pay assistance counts toward deductibles, keeping patients adherent to therapy.